Chloromethane’s functional reach extends beyond silicones and healthcare. Historically, it was used as a refrigerant (known as R-40), though its flammability curtailed this role in favor of safer alternatives. It remains relevant in specialized cooling applications and as a raw material in restricted refrigerant chemistries.

The compound also serves as a solvent and extractant of oils, resins, and rubber processing agents. It aids in the making of butyl rubber and facilitates petroleum refining processes.

Moreover, chloromethane functions as a propellant and blowing agent—particularly in foam manufacture—where its volatility and expansion characteristics support effective cellular structure formation.

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